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Image Search Results
Journal: Journal of Neuroscience
Article Title: Dual Presynaptic Control by ATP of Glutamate Release via Facilitatory P2X1, P2X2/3, and P2X3 and Inhibitory P2Y1, P2Y2, and/or P2Y4 Receptors in the Rat Hippocampus
doi: 10.1523/jneurosci.0628-05.2005
Figure Lengend Snippet: Figure 2. The facilitatory effect of ATP analogs is mediated by P2X receptors, whereas the inhibitory effect is mediated by P2Y receptors. A, The facilitatory effect of 60 M ,-ImATP was reverted in the presence of NF023 (10 M; a selective P2X1, P2X2/3, and P2X3 receptor antagonist)andnotmodifiedbyeitherRB2(10M;aP2Yreceptorantagonist)orMRS2179(10 M;aselectiveP2Y1receptorantagonist).B,Theinhibitoryeffectof10M,-ImATPwasnot modified by NF023 but was prevented by RB2 and attenuated by MRS2179. *p 0.05 com- pared with the first bar from left in A and B. The results are mean SEM of four to six experiments.
Article Snippet: The antibodies against P2X1,
Techniques: Modification
Journal: Journal of Neuroscience
Article Title: Dual Presynaptic Control by ATP of Glutamate Release via Facilitatory P2X1, P2X2/3, and P2X3 and Inhibitory P2Y1, P2Y2, and/or P2Y4 Receptors in the Rat Hippocampus
doi: 10.1523/jneurosci.0628-05.2005
Figure Lengend Snippet: Figure 3. ,-ImATP modulates the evoked [Ca 2]i transients in a biphasic manner through inhibitory P2Y and facilitatory P2X receptors in rat hippocampal nerve terminals. A, Representative experiment of the increase and decrease of the K (20 mM)-evoked[Ca 2]icausedby,-ImATPat60and30M,respectively.Allexperimentswereperformedinthepresenceof50 nM ZM241385 and 50 nM DPCPX to exclude P1 receptor-mediated effects. B, The facilitatory effect of 60 M ,-ImATP was preventedbyPPADS(20M;anonselectiveP2receptorantagonist)andbyNF023(10M;aselectiveantagonistofP2X1,P2X2/3, andP2X3receptors)andnotmodifiedbyRB2(10M;apreferringantagonistofP2Yreceptors).C,Theinhibitoryeffectof30M ,-ImATP was not modified by NF023 but was prevented by PPADS and attenuated by RB2. The percentage variations of [Ca 2]iarerelativetocontrolvalues(B,C).*p0.05comparedwith0%.**p0.05comparedwithfirstbarfromleftinBand C. The results are mean SEM of four to six experiments.
Article Snippet: The antibodies against P2X1,
Techniques: Modification
Journal: International Journal of Molecular Sciences
Article Title: Analysis of Spatial and Temporal Distribution of Purinergic P2 Receptors in the Mouse Hippocampus
doi: 10.3390/ijms22158078
Figure Lengend Snippet: List of primary and secondary antibodies.
Article Snippet:
Techniques: Plasmid Preparation